Traditional Uses: Traditionally used by Native Americans and in European herbal medicine as a gentle nervine for anxiety, nervous tension, insomnia, neuralgia, and historically for epilepsy and rabies (hence the name “mad-dog weed”).
Potential Benefits: May help reduce anxiety and improve overall mood disturbance (including depression-dejection and vigor-activity), with some research suggesting anticonvulsant and neuroprotective properties.
Warnings: Avoid during pregnancy (may stimulate uterine contractions and affect hormones); rare cases of liver injury have been reported but often linked to adulteration with germander, and high doses may cause giddiness, confusion, or seizures.
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